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Author

Juergen A. Knoblich

2 papers indexed here

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Open access Sep 2026

Cerebral organoids recapitulate interneuron chain migration in the human cortex

It is shown that human cerebral organoids cultured for over six months recapitulate postnatal interneuron migration, enabling its mechanistic and genetic dissection and mechanistic analysis of previously inaccessible aspects of postnatal human brain development and their contributions to neurodevelopmental disease.

Sakurako Nagumo Wong, M. Noble, M. Fischer et al. · 0 citations
Open access Oct 2026

Connectomics by Sequencing Reveals Self-Organizing Principles of Neuronal Networks in Cerebral Organoids

Functional neural networks emerge as developing neurons form synaptic connections. Revealing how these connections are organized and perturbed in disease requires linking single-neuron connectivity to molecular state across thousands of networks, which is challenging with current methods. We developed COSCO (Connectomi...

Ábel Vértesy, R. Najm, Bálint Doleschall et al. · 0 citations

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