Review
Open access
2026
Prognostic impact of her2-low status in patients with breast cancer: a systematic review of the literature
Introduction: Breast cancer (BC) is a biologically heterogeneous disease and HER2 expression presents important prognostic implications. Recently, the HER2-low BC has been recognized, defined as HER2 immunohistochemistry (IHC) 1+ or 2+ without gene amplification, whereas HER2-zero tumors show no detectable expression....
Deborah Abucarma Soares, M. E. T. Mendes, A. Carvalho et al.
· Mastology · 0 citations