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Author

Júlia Belone Lopes

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Jul 2026

Clinicopathological factors associated with brain metastases development among breast cancer patients receiving neoadjuvant chemotherapy

Among patients treated with NAC for early-stage BC, residual nodal disease, inflammatory BC, and HER2+ or triple-negative subtype are associated with a higher risk of BrM development and whether BrM screening is warranted among patients with these high-risk features warrants evaluation.

Jie Zhu, I. Fernandes, Júlia Belone Lopes et al. · 0 citations
Open access Aug 2026

RMTC-07 OBESITY AND RISK OF BRAIN METASTASES AMONG PATIENTS DIAGNOSED WITH EARLY-STAGE BREAST CANCER: A POPULATION-BASED COHORT STUDY

Abstract Background Obesity is characterized by chronic low-grade systemic inflammation and altered metabolic signaling, which may disrupt periphery-to-brain communication and compromise central nervous system interfaces. These obesity-associated inflammatory perturbations may influence tumor seeding and the phenotypic...

C. Murphy, Bo Zhang, Júlia Belone Lopes et al. · 0 citations

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