Background/Objectives: AP-2 transcription factors are increasingly recognized as key regulators in cancer biology. The TFAP2E gene, which encodes the AP-2ε transcription factor, remains understudied in cancer compared with other AP-2 family members. The scarcity of studies examining potential AP-2ε targets and related...
D. Kołat, Julia Gałęziewska, Paulina Buczek et al.· Cancers· 0 citations
Parasites and allergic diseases are linked by a complex, bidirectional relationship shaped by long-term host–parasite coevolution. This review discusses how different parasites may either promote or attenuate allergic responses through immunological, epithelial, and microbiome-mediated mechanisms. IgE-mediated immunity...
Kacper Packi, D. Świerczewski, Sylwia Klimczak et al.· Antonie van Leeuwenhoek· 0 citations
This review examines how stemness-associated signaling pathways, including Hedgehog, Notch, and Wnt/ β -catenin, interact with DDR programs to promote CSC survival under genotoxic stress, and summarizes current and emerging therapeutic strategies targeting CSC-specific DDR dependencies.
M. Kciuk, Julia Gałęziewska, Weronika Kruczkowska et al.· Oncology Research· 0 citations
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