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Júlia Vitória Medeiro Birtche

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Review Open access Aug 2026

SPIRONOLACTONE VERSUS DOXYCYCLINE FOR MODERATE ACNE IN ADULT WOMEN: EFFICACY, MENSTRUAL IRREGULARITY, AND HYPERKALEMIA RISK — A SYSTEMATIC REVIEW

Introduction: Oral antibiotics are effective for inflammatory acne but prolonged use contributes to antimicrobial resistance. Spironolactone offers a nonantibiotic systemic alternative for adult women, although comparative efficacy and concerns about menstrual irregularity and hyperkalemia influence prescribing. Object...

Marisa Peçanha de Barros, Júlia Vitória Medeiro Birtche, Pedro Yuri da Silveira et al. · 0 citations

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