Open access
Oct 2026
Enhanced liver regeneration via targeted mRNA delivery for partial in vivo reprogramming.
Recent studies indicate that injury-induced dedifferentiation generates transient regenerative progenitors (TRPs), which support tissue repair across multiple organs, including the liver. In vivo partial reprogramming using Yamanaka factors (Oct4, Sox2, Klf4, and c-Myc; OSKM) produces intestinal TRPs closely resembling...
Beom-Ki Jo, Young Seok Song, Woohyun Song et al.
· Cell Reports Medicine · 0 citations