Jun-Cai He

Photoreceptor outer segments promote the accumulation of lipid droplets in microglia by reprogramming lipid metabolism

Retinal degeneration (RD) ultimately leads to blindness owing to progressive photoreceptor loss. Previous studies have shown that microglia play a key role in photoreceptor degeneration through multiple phenotypes. However, the determinants of their phenotypic regulation remain unclear. As microglia migrate into the su...