Open access
Jan 2026
Pachymic Acid Accelerated Diabetic Ulcer Healing by Enhancing Macrophage Efferocytosis via the MEK/ERK/TGFβ1 Signaling Axis.
OBJECTIVE Diabetic ulcers (DUs) are severe and prevalent complications of type 2 diabetes, characterized by impaired macrophage efferocytosis and sustained chronic inflammation within the wound microenvironment. Pachymic acid (PA) is a natural triterpenoid with potent anti-inflammatory and immunomodulatory properties....
Li Wang, Gao-Jie Zhang, Yi-Le Cheng et al.
· Journal of Diabetes Research · 0 citations