A Digital Twin Framework for Per-Fraction Prediction of Normal Tissue Toxicity in Radiotherapy of Non-Small Cell Lung Cancer
Background/Objectives: Stereotactic body radiation therapy (SBRT), often delivered in 3–5 fractions, is a highly effective treatment strategy for early-stage non-small cell lung cancer (NSCLC) in medically inoperable patients. Biology-guided radiotherapy (BGRT), a PET-guided SBRT, enables acquisition of patient-specifi...