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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Jun Fei

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Review Open access Aug 2026

Mitochondrial dysfunction as a key mediator of endplate chondrocyte senescence: emerging insights and targeted interventions.

Intervertebral disc degeneration (IVDD) is a leading global cause of chronic pain and functional impairment. The senescence of endplate chondrocytes (EPCs) associated with the IVDD cascade, with mitochondrial homeostatic imbalance serving as the central pathological key mediator. EPCs inhabit a physiological niche defi...

Ruohui Tang, Jin-Hua Yin, Shidan Li et al. · 0 citations

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