Getah virus (GETV) is an emerging mosquito‐borne zoonotic alphavirus that poses a threat to multiple animal species, particularly pigs, and carries significant public health implications. Nevertheless, the molecular evolution and pathogenicity of circulating GETV strains in China remain incompletely defined. In this st...
Zhao-Ying Xiang, Xing-Chen Wang, Yuchen Huang et al.· Transboundary and Emerging D...· 0 citations
1B9 provides a useful reagent for studying the expression, localization, and antigenic properties of pB169L, and is broadly conserved across several ASFV genotypes.
Zhi-Ying Cui, Jia-Ning Feng, Miao-Miao Ye et al.· Frontiers in Microbiology· 0 citations
The first identification of a natural GETV variant isolated from the brain of diseased piglets is reported, identifying a highly conserved E1 stem motif as a critical regulator of GETV virulence, offering a strategic target for developing attenuated vaccines against GETV and other alphaviruses.
Zhao-Ying Xiang, Gan-Bo Li, Jia-Yi Wang et al.· Virulence· 0 citations
In vitro findings reveal that ASFV dismantles host phagolysosomal acidification, thereby neutralizing the microbicidal potential of infected macrophages and potentially converting them into a permissive niche for secondary bacterial pathogens.
Detailed immune responses in a PRRSV vaccination–challenge model spanning complete, partial, and non‐protection outcomes are defined and insights for rational PRRSV vaccine design are provided.
C. Kong, Siang Chen, Maolin Li et al.· Advancement of science· 0 citations
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