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Open access Sep 2026

Predicted STAT1-BRAF and IRF7-MET Regulatory Links Are Associated with MAPK Pathway Reactivation and Targeted Therapy Resistance in Melanoma

Resistance to BRAF inhibitors (BRAFi), alone or with MEK inhibitors (MEKi), limits durable responses in BRAF-mutant melanoma. To characterize resistance-associated cell-state evolution, we analyzed 674 melanoma cells from six mice bearing tumors from a single patient-derived BRAF V600E-mutant melanoma xenograft (PDX) l...

Hao Fu, Meng-Yao Wang, Hai-Bo Zhu et al. · 0 citations
Review Sep 2026

Network Analysis of Spiritual Care Perceptions and Empathy in Baccalaureate Nursing Students: A Holistic Nursing Perspective.

Study PurposeTo analyze the internal associations between spiritual care perceptions and empathy among baccalaureate nursing students.Design and MethodsA cross-sectional study was conducted with 237 baccalaureate nursing students from a medical university located in Southeast China between April and May 2024. Data were...

Dan-Dan Wu, Jun He · 0 citations

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