Is postoperative adjuvant therapy necessary for esophageal cancer patients with pathological complete response after neoadjuvant treatment?
BACKGROUND Current National Comprehensive Cancer Network (NCCN) guidelines recommend omission of adjuvant therapy in esophageal cancer patients achieving pathological complete response (pCR) following neoadjuvant treatment. However, 20-40% of these patients experience disease recurrence, potentially indicative of resid...