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Author

Jun Hu

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Aug 2026

Ultrasensitive circulating tumor DNA analysis improves detection of molecular residual disease in locally advanced esophageal cancer.

PURPOSE Circulating tumor DNA (ctDNA) could be a powerful prognostic biomarker for patients with locally advanced esophageal cancer but higher sensitivity is needed. An ultrasensitive test could enable improved treatment decision-making by accurately identifying patients with residual disease. EXPERIMENTAL DESIGN 331...

J. Rhoades, Anuj K. Patel, K. Xiong et al. · 0 citations
Open access Aug 2026

Pharmacological readthrough and base editing for ANK1 nonsense mutations in an erythroid model of hereditary spherocytosis

Findings provide exploratory proof-of-concept for targeted molecular intervention in ANK1 nonsense mutation-associated HS, highlighting TRIDs and ABEs as mechanistically distinct strategies with complementary strengths and limitations and suggesting their relative utility may depend on mutation-specific and clinical co...

Shan Li, Juan Li, Wen-Jing Shi et al. · 0 citations

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