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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Jun-Hu Wan

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Sep 2026

ADP Inhibits Macrophage Senescence via the AMPK/KLF10 Pathway in Systemic Lupus Erythematosus

Lupus nephritis (LN) is a critical complication of systemic lupus erythematosus (SLE) and a leading cause of mortality in those affected. Abnormal energy metabolism of macrophages is closely associated with LN pathogenesis. Adenosine diphosphate (ADP) is known to regulate macrophage proinflammatory function; however, i...

Shuang Yang, Zhu-Li Li, Yan-Teng Zhao et al. · 0 citations
Open access Aug 2026

AL398, A Novel NSUN6 Inhibitor, Attenuates Epithelial‐Mesenchymal Transition and Metastasis in Endometrial Cancer by Abrogating m5C‐Dependent Stabilization of Snail mRNA

It is demonstrated that the m5C methyltransferase NSUN6 is significantly upregulated in EC tissues, and its expression correlates with higher tumor grade and unfavorable prognosis, and a proof‐of‐concept inhibitor, AL398, is provided, laying the groundwork for the development of first‐in‐class RNA methylation‐targeted...

Xiangzhuan Zhao, Lin-Lin Yang, Huanxiang Chen et al. · 0 citations

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