Open access
Sep 2026
Artesunate Targets MBL2 to Modulate the TLR4/NRF2/HO‑1 Axis and Ameliorate Podophyllotoxin‑Induced Liver Injury
Background Drug-induced liver injury (DILI) presents a significant clinical challenge with limited preventive and therapeutic options. Artesunate (ART) holds potential for DILI treatment; however, its precise hepatoprotective mechanisms and direct molecular target(s) remain unclear. Methods We evaluated ART in a podoph...
Ming-Yue Wei, Jun-Jie He, Yan-Zhao Zhang et al.
· Drug Design, Development and... · 0 citations