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Author

Jun-Kang Ren

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Aug 2026

Bridging DNA damage and cGAS-STING activation: Platinum (IV) prodrugs as single-molecule chemo-immunotherapeutics.

Cisplatin-based chemotherapy remains a cornerstone in cancer treatment, yet its clinical utility is often hampered by severe systemic toxicity and the cold immune microenvironment of many tumors. To address these challenges, we leveraged the kinetically inert nature and structural versatility of the Platinum (IV) [Pt (...

Jun-Kang Ren, Jia-Ni Wu, Xin-Yu Dai et al. · 0 citations

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