Author

Jun Kim

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Review Open access Sep 2026

From Dual Targeting to Clinical Validation: A Translational Framework for Bispecific Antibody–Drug Conjugates

Bispecific antibody–drug conjugates (bsADCs) are being developed to address limitations of conventional ADCs, including heterogeneous antigen expression, insufficient tumor–normal discrimination, and suboptimal intracellular trafficking. This review evaluates bsADCs from a preclinical-to-clinical translational perspect...

Jun Kim, Seounghun Kang · International Journal of Mol... · 0 citations

Review Open access Jul 2026

Emerging Precision Therapeutic Strategies in Pancreatic Ductal Adenocarcinoma: KRAS Targeting, DDR Vulnerabilities, Immune Redirection, and Tumor Microenvironment Remodeling

Recent advances indicate that therapeutic resistance in PDAC is a dynamic process involving interconnected oncogenic, genomic, stromal, metabolic, and immune mechanisms, and future progress will require biologically informed treatment frameworks integrating complementary therapeutic modalities according to baseline tum...

Jun Kim, Seounghun Kang · Pharmaceutics · 0 citations

Review Open access Aug 2026

Emerging Therapeutic Strategies in Small-Cell Lung Cancer: From Adaptive Resistance to Precision Therapy

The evolving biological basis of therapeutic resistance is examined and how emerging treatment strategies may be integrated into biologically informed clinical development is discussed to improve patient selection, guide therapeutic sequencing, and increase the durability of treatment benefit in extensive-stage SCLC.

Jun Kim, Seounghun Kang · Pharmaceuticals · 0 citations