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Author

Jun Lu

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Review Open access Aug 2026

MicroRNA-phytochemical interactome targeting thioredoxin-interacting protein: a narrative review at the nexus of RNA therapeutics, cancer biology, and metabolic regulation

This narrative review discussed emerging trends on phytochemical-mediated regulation of TXNIP-associated miRNAs, including miR-148b, miR-33a/b, miR-17-5p, miR-224, and miR-20a, with particular emphasis on the conserved miRNA seed region as the principal determinant of target recognition.

Peter Chinedu Agu, P. Aja, C. Ofor et al. · 0 citations
Jul 2026

Construction and systematic engineering of Saccharomyces cerevisiae for efficient de novo biosynthesis of pentostatin.

Pentostatin is a potent adenosine deaminase inhibitor, yet its industrial application is hindered by low extraction yields and complex chemical synthesis. Here, we report an efficient de novo biosynthesis platform for pentostatin in Saccharomyces cerevisiae. Starting with the heterologous expression of cns3 from Cordyc...

Ming-Zhe Bai, Zhiyi Liu, Chao-Zhong Wang et al. · 0 citations

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