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Author

Jun-Peng Huang

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Aug 2026

Cancer-Associated Fibroblasts-Derived Exosomal METTL3 Drives Breast Cancer Malignancy by Eliciting PABPN1 m6A Modification.

A novel CAFs-to-cancer cell communication axis where exosomal METTL3 promotes BC progression and immune escape via m6A-dependent upregulation of PABPN1 is identified, highlighting this pathway as a promising therapeutic target.

Jun-Peng Huang, Shu-Ming Zhang, Dan-Feng Zhang et al. · 0 citations
Conference Open access Sep 2026

4DVarGen: A 4D Variational-Inspired Generative Model for Eddy-Resolving Surface Ocean Reconstruction

4DVarGen is proposed, a 4DVar-inspired generative framework for reconstructing sea surface variable fields at eddy-resolving scales from sparse remote-sensing observations that establishes a mathematical equivalence between 4DVar and an observation-guided denoising process.

Jun-Peng Huang, Wu-Xin Wang, Xiao-Yong Li et al. · 0 citations

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