Author

Jun-Qian Zhao

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Aug 2026

Fragment-based discovery of novel Baicalein derivatives as triple-target 3CLpro/PLpro/RdRp inhibitors against SARS-CoV-2.

The rapid evolution of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and the emergence of drug resistance necessitate the development of multi-target antiviral therapeutics. This study aimed to computationally design a novel triple-target inhibitor derived from the natural flavonoid Baicalein, targeting...

Di Han, Hong-Kun Yang, Yi-Fan Wang et al. · Bioorganic chemistry (Print) · 0 citations

Preprint Aug 2026

ClueWeaver: Reward-Guided Dual-Agent Evidence Reasoning for Compact LLMs on Literary Long Narratives

Experiments across multiple long-context narrative question answering and claim verification settings show that ClueWeaver substantially improves local end-to-end language models while providing evidence coverage and paragraph-referenced reasoning traces.

Ji-Hao Zhu, Zhi-Wei Yang, Wen-Xiao Zhang et al. · 0 citations