Author

Jun Wang

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Open access Jul 2026

Cross-Species Efficacy of Combinatorial Gene Therapy for Osteoarthritis and Correction of Neuro-Inflammatory Pain Mechanisms

A single intra-articular injection of a combinatorial gene therapy slows OA progression and reduces pain in small and large animal models, and identifies neuroinflammatory signatures for correction of disease progression and pain.

E. Secor, Jun Wang, Zelong Dou et al. · bioRxiv · 0 citations

Aug 2026

Cell Type-Specific Isoform Function Prediction by Multiplex Heterogeneous Network

Sequence-importance analysis highlights critical amino-acid regions and shows that domains annotated with the same function can exhibit distinct importance profiles across spliced isoforms, providing new insights into cell-type-specific isoform functionality and establishing cIsoFun as a practical tool for single-cell...

Tong-Hui Gu, Han-Wen Luo, Yue-Qun Wang et al. · IEEE Transactions on Computa... · 0 citations