Aug 2026
PTBP1 controls oncogenic transcript processing and maintenance of acute myeloid leukemia.
Findings demonstrate that PTBP1 supports AML proliferation by fine-tuning the expression and splicing of AML-essential genes, providing a workflow for systematically annotating RNA-associated protein dependencies in cancer.
Zhendong Cao, Kurtis N. McCannell, Si-Xiang Yu et al.
· Leukemia · 0 citations