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Author

Junxia Zheng

3 papers indexed here

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Open access Sep 2026

Structure-Guided Covalent Design and Biological Evaluation of Glycidamido-Leucinamide Antivirulence Agents Against Pseudomonas aeruginosa

Antimicrobial resistance in Pseudomonas aeruginosa has intensified the need for therapies that do not rely solely on bactericidal activity. Antivirulence agents attenuate pathogenic functions and may complement conventional antibiotics. The elastase LasB is a major quorum-sensing (QS)-controlled virulence factor of P....

Xiao-Qing Mu, Yu-Jing Huang, Hao-Ming Chen et al. · 0 citations
Sep 2026

Mesona chinensis Benth polyphenols ameliorate type 2 diabetes mellitus in mice through coordinated regulation of gut microbiota, metabolic profiles, and host metabolic-inflammatory responses.

BACKGROUND Mesona chinensis Benth polyphenols (MCP) have demonstrated potential anti-diabetic activity. However, the underlying mechanisms involved in their metabolic regulation remain incompletely understood. OBJECTIVE This study aimed to investigate the anti-diabetic effects of MCP in HFD/STZ-induced type 2 diabete...

Chu-Shan Chen, Qing-Hui He, Hao-Heng Cao et al. · 0 citations
Open access Aug 2026

Chemical Characterization, Network Pharmacology, Molecular Docking, and Comparative Anti‐Colitic Activity of Polar and Nonpolar Fractions From Raphanus Sativus L. Seeds

In a dextran sulfate sodium‐induced murine colitis model, RSEE demonstrated superior efficacy in reducing disease activity and restoring mucosal barriers compared to RSO, with sinapine serving as the key material basis for treating colitis via oxidative stress modulation.

Wenlin Chen, Yu-Jing Huang, Xin Yu et al. · 0 citations

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