Jun-Xiu Zhou

Combining network toxicology with in vitro and in vivo experimental validation to investigate the toxicological mechanisms of phthalate exposure in promoting osteosarcoma.

Phthalates (PAEs), as ubiquitous persistent organic pollutants and typical endocrine disruptors (EDCs), have been shown in epidemiological studies to be associated with the development of osteosarcoma (OS). However, the molecular mechanisms by which PAEs regulate the occurrence and progression of OS remain unclear. Acc...