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Author

Jun-Yun Huang

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Open access Oct 2026

Serum exosomal DDX17 in the diagnosis and action mechanism of hepatocellular carcinoma

This study aimed to explore DDX17 protein expression as a diagnostic biomarker of hepatocellular carcinoma (HCC) and its roles in the occurrence and development of HCC. The proteomics sequencing method was applied to study nine samples of exosomes separated from HCC tissues and corresponding normal non-cance...

De-Fa Huang, Ming-Hong Zhao, Mei-Jin Liu et al. · 0 citations
Review Open access Sep 2026

Unlocking Parkinson’s disease: harnessing the untapped potential of fatty acid metabolism in disease pathogenesis

Parkinson’s disease (PD) is the second most common neurodegenerative disorder, and its rising incidence poses a growing burden on productivity and healthcare systems, particularly in the context of global population aging. Despite substantial advances in research, the pathogenesis of PD remains incompletely understood,...

Rong Hu, Ya-Ru Song, Ting Y. Liu et al. · 0 citations
Open access Aug 2026

A dual A-to-Y and G-to-Y base editor and a four-base concurrent hypermutator in mammalian cells

A compact dual base editor “A&GBE” is engineer by fusing a deaminase and glycosylase with nickase Cas9 to enable concurrent adenine and cytosine editing and develops quadruple base mutating modules (QBMM) that enables simultaneous mutation of all four types of nucleotide bases.

Na Zhao, J. S. Olajide, Zhihong Guan et al. · 0 citations

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