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Review Open access Oct 2026

Probiotics in type 1 diabetes: immunomodulatory mechanisms and the unresolved question of clinical efficacy

Type 1 Diabetes (T1D) is a common autoimmune disease worldwide, which is associated with imbalanced gut microbiota. Intestinal dysbiosis plays a key role in the pathogenesis of T1D, and it may affect immune tolerance and autoimmune responses of pancreatic islet β-cells. As a potential immunomodulator, probiotics can he...

Simiao Chen, Lu Wang, Shuo-Tong Zhang et al. · 0 citations

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