Two-photon photodynamic induction of PANoptosis and immunogenic cell death for precision tumor eradication using a dual-organelle-targeted STING agonist.
Triple-negative breast cancer (TNBC) remains a formidable clinical challenge owing to its aggressive metastatic behavior and the absence of well-defined therapeutic molecular targets. Although photodynamic therapy (PDT) holds immense promise, its efficacy is often limited by the aggregation-caused quenching (ACQ) of co...