Review
Open access
Aug 2026
The role of the neuro-immune-bone axis in osteoporosis: from bone remodeling imbalance to multi-system interactions
Osteoporosis is a systemic metabolic bone disease characterized by decreased bone mass, destruction of bone microstructure, and increased risk of fractures. Traditional views mainly attribute it to an imbalance between osteoblast-mediated bone formation and osteoclast-mediated bone resorption, but increasing evidence s...
Yupeng Zhang, Junchen Lu, Guojun Deng et al.
· Frontiers in Immunology · 0 citations