Modified citrus pectin orchestrates hepatic redox homeostasis through an Alistipes dispar-nicotinamide-sirtuin 1 axis to mitigate metabolic dysfunction-associated steatotic liver disease.
BACKGROUND Modified citrus pectin (MCP) is a bioactive functional component with potential metabolic benefits, but its therapeutic mechanisms in metabolic dysfunction-associated steatotic liver disease (MASLD) remain unclear. PURPOSE To determine whether MCP alleviates MASLD through gut microbiota remodelling and to...