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Author

Junjing Xiong

1 paper indexed here

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Open access Jul 2026

Brazilin attenuates methylglyoxal-induced endothelial injury by enhancing eIF5A hypusination and inhibiting the AMPK/mTOR-mediated autophagy/apoptosis axis in vitro and in vivo

Methylglyoxal (MGO), a glycolytic metabolic byproduct and major precursor of advanced glycation end products (AGEs), accumulates and is critically involved in diabetes, particularly in diabetic vascular complications. In endothelial cells (ECs), MGO has been implicated in oxidative stress and inflammatory responses, an...

Yu Liang, Jinxiang Chen, Haiyang Li et al. · 0 citations

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