Author

Jürgen Popp

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Open access Oct 2026

Label-free identification and classification of leukocyte subpopulations in peripheral blood smears by optical photothermal infrared spectroscopy

The differential count of leukocyte subpopulations from peripheral blood smears remains a cornerstone of clinical hematology but relies on staining protocols or flow cytometry, that introduce variability and obscure native biochemistry. This study presents label-free workflows that distinguish leukocytes from erythrocy...

Shravan Raghunathan, S. Piehler, Cornelia Reuter et al. · bioRxiv · 0 citations

Open access Sep 2026

Passively Targeted Polymeric Nanocarrier Delivering STAT1 siRNA to the Liver Ameliorates Steatohepatitis and Fibrosis in the Thioacetamide Mouse Model.

Liver fibrosis is a major complication of chronic liver injury, driven in part by Signal Transducer and Activator of Transcription 1 (Stat1). This study evaluated passively liver-targeted polymeric nanocarriers delivering Stat1 siRNA (siSTAT1) to treat steatohepatitis and fibrosis in a thioacetamide (TAA) mouse model....

Klea Mehmetaj, Antea Jorgo, Wanling Foo et al. · Biomacromolecules · 0 citations