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Justin A. Ling

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Aug 2026

Human nuclear ribomes reveal DNA-embedded ribonucleotides as epigenetic modulators of transcription-associated DNA supercoiling.

A non-random nuclear "ribome," the genome-wide landscape of embedded rNMPs, enriched in GC-rich regions, regulatory elements, and telomeres, is revealed, revealing a connection between ribonucleotide processing and transcription-associated DNA topology in human cells.

Deepali L. Kundnani, Yeunsook Lee, Taehwan Yang et al. · 0 citations

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