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Justin Boone

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Open access Aug 2026

Task geometry alignment enables parameter independent and accurate genomic search

TGAlign, an expert-parameter-independent tool that tiles reference databases to match query lengths, encodes sequences into gap-robust syncmer profiles, and indexes them for high-speed Approximate Nearest Neighbor (ANN) search is implemented, providing a robust and scalable framework for post-alignment genomic search.

Justin Boone · 1 citation

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