Open access
Sep 2026
Novel Lomefloxacin–Triazole Hybrids: Design, Synthesis and In Vitro Antiproliferative Activity in Breast, Melanoma and Colon Cancer Cell Lines
In recent years, extensive research has focused on fluoroquinolone–triazole hybrids, with particular emphasis on structural modifications of ciprofloxacin. In the present study, novel derivatives of lomefloxacin with a 1,4-disubstituted-1,2,3-triazole moiety were designed, synthesised, and biologically evaluated at the...
Justyna Nowakowska, Zuzanna Rzepka, A. Bąk et al.
· Biomolecules · 0 citations