Aging is a multifactorial biological process characterized by progressive alterations in cellular homeostasis, metabolic regulation, immune function, and neurological integrity, contributing to chronic disease, functional decline, and reduced healthspan. Natural bioactive compounds are increasingly investigated as pote...
Siriporn Namwongsa, Jutarop Phetcharaburanin, S. Boonlue et al.· Pharmaceuticals· 0 citations
Trimethylamine N-oxide (TMAO), a gut microbiota-derived metabolite, has been implicated in atherosclerosis and adverse cardiovascular outcomes, but prospective data on lower extremity arterial disease (LEAD) in Asian populations remain limited. We conducted a single-center prospective cohort study of 155 Thai patients...
N. Kulthamrongsri, Jutarop Phetcharaburanin, Supranee Phanthanawiboon et al.· Scientific Reports· 0 citations
Investigation of how neuronal ERO1L elevation reshapes cellular homeostasis before overt dysfunction in Drosophila melanogaster establishes a pre-symptomatic state in which proteostatic and metabolic adaptation coexists with early vulnerability of nuclear and RNA-homeostasis pathways, preceding overt oxidative stress a...
L. Lo Piccolo, Ranchana Yeewa, Puttachat Poound et al.· bioRxiv· 0 citations
This review synthesizes current mechanistic and translational evidence to conceptualize the gut microbiome as an organ‐like functional system, delineate its structural and functional organization, and propose a framework for mapping, modeling, and therapeutically targeting microbiome‐derived circuits to support precisi...
Yang Bi, Wei-Bin Song, Maria Glymenaki et al.· iMeta· 0 citations
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