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Jyotirmayee Dash

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Sep 2026

Small Molecule Modulation of TERRA RNA Quadruplex Reprograms ALT-Telomere Maintenance.

Telomeric repeat-containing RNA (TERRA) plays a central role in telomere maintenance in telomerase-negative cancers that employ the alternative lengthening of telomeres (ALT) pathway; however, its RNA G-quadruplex (rG4) structures remain underexplored as chemical targets. Here, we report a structure-guided approach to...

Tathagato Bhattacharyya, Sarmistha Pal, Maximillian Braun et al. · 0 citations

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