Author

Jyotsna Singh

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Open access Nov 2026

Plasma Cell-Free DNA-Based Next-Generation Sequencing for Molecular Profiling of Diffuse Gliomas

To evaluate the utility of plasma-derived cell-free DNA (cfDNA) using targeted next-generation sequencing (NGS) for molecular profiling of diffuse gliomas (DG) by assessing concordance with matched tumor tissue DNA, mutation profiles, variant allele frequencies, therapeutically actionable alterations, and surviva...

Swati Singh, Jyotsna Singh, S. Bhardwaj et al. · Neuro-Oncology Advances · 0 citations

Open access Aug 2026

79 Diagnostic Utility of DNA Methylation Profiling in CNS Tumors: A Comparative Study of FFPE and Fresh-Frozen Tissues

DNA methylation–based classification has become an essential adjunct to histopathology in central nervous system (CNS) tumor diagnostics. Although both fresh-frozen and formalin-fixed paraffin-embedded (FFPE) tissues are used for methylation profiling, comparative real-world data on their diagnostic performance r...

Jyotsna Singh, S. Mansoori, A. Suri et al. · Neuro-Oncology · 0 citations