Abstract B011: HMGA2 controls fibroblast skewing and immune infiltration in basal pancreatic cancer
The basal-like subtype of pancreatic ductal adenocarcinoma (PDAC) is associated with poor outcomes and increased chemoresistance. Expression of high mobility group AT-hook 2 (HMGA2), a chromatin architectural protein, marks basal PDAC cells. Recent efforts to understand the tumor microenvironment (TME) of PDAC have e...