Revealing Aβ peptide isoforms, including post-translationally modified species, through Cu(II)-mediated electrochemical profiling using a dual-electrode set-up.
Amyloid-β (Aβ) peptides constitute key molecular signatures associated with Alzheimer's disease (AD), the most common neurodegenerative disorder. The high diversity of the Aβ peptide family, including N-terminal truncations and post-translational modifications, poses a major analytical challenge, as closely related Aβ...