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Author

K. Brosch

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Open access Oct 2026

Distinct profiles of white matter diffusivity in obesity and bipolar disorders: An ENIGMA bipolar disorders study in 2166 individuals

Abstract Background Bipolar disorders (BD) are associated with a wide range of brain white matter abnormalities, but results vary across studies. This heterogeneity likely relates to effects of additional clinical/diagnostic variables, including medications and obesity, on white matter in BD. In this mega-analysis, we...

Lorielle M. F. Dietze, Sean R. McWhinney, P. Favre et al. · 0 citations
Open access Aug 2026

Negative expectations in major depression: Association with brain structure and course of illness.

BACKGROUND Negative expectations towards the future are frequently observed in patients with major depressive disorder (MDD) and linked to less favourable outcomes like worse treatment response and suicidal behaviours. Despite clinical significance, the neurobiological underpinnings of negative expectations remain larg...

Laila Noor, F. Stein, K. Brosch et al. · 0 citations
Open access Sep 2026

Cognitive Reserve as a Stratification Factor for Cognitive Impairment and Disease Progression in Major Depressive Disorder.

The moderating effect of CR on the brain network-cognition association provides a neurobiological rationale for this vulnerability and supports incorporating CR into routine clinical assessment to guide risk stratification and personalized treatment planning.

M. Gruber, Henrike Renaud, M. Mauritz et al. · 0 citations
Aug 2026

ACES: ascertaining diagnosis classification with elicited speech in individuals with heterogeneous, comorbid psychiatric disorders.

It is suggested that a brief, explainable speech-based assessment may be able to identify individuals who need further evaluation for psychiatric disorders and external validation, bias auditing, and deployment studies are warranted to assess clinical impact.

Sunny X. Tang, Jiefei Li, K. Brosch et al. · 0 citations

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