K. Chen

Modular synthesis of unsymmetrical all-carbon tetrasubstituted alkenes via Pd-catalyzed multi-component coupling.

Tetrasubstituted alkenes constitute privileged architectures in material science, biomedicine, and chemistry. However, achieving their stereocontrolled synthesis-especially for molecules with four distinct substituents-remains a formidable challenge, as conventional methods lack the necessary modularity and stereoselec...