Apigenin And Ε-Viniferin from Dioscorea Transversa Leaves: Isolation and in Silico Evaluation Against HPV16 E6 And Inflammatory and Angiogenic Targets
Background and objectives: Long-term infection with HPV16 is the main cause of cervical cancer, and the viral E6 protein contributes by recruiting the host ligase E6AP, which marks p53 for destruction. Leaf extracts of Dioscorea transversa R. Br. have been reported to contain more polyphenols and to show stronger anti-...