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Open access Sep 2026

Prognostic Value of Composite Biomarkers Integrating Insulin Resistance and Coronary Inflammation for Major Adverse Cardiovascular Events in Post-PCI Patients with Coronary Artery Disease Across Glycemic Status: A Prospective Cohort Study

Background The study aimed to assess the prognostic utility of composite Insulin resistance (IR)- various inflammation biomarkers for predicting poor outcomes in coronary artery disease (CAD) patients stratified by glycemic status. Methods The prospective cohort included 1947 CAD patients undergoing PCI with pre-proced...

Zi-Xiang Ye, Chen-Yu Liu, En-Min Xie et al. · 0 citations
Open access Aug 2026

Intensified lipid-lowering strategies and their effect on atherogenic and metabolic markers in coronary artery disease: a prospective cohort study.

Triple LLT was associated with more comprehensive control of atherogenic lipid markers, with a similar trend for IR markers, and stratified intensification of LLT may support individualized risk-factor management in CAD, although cardiovascular outcome benefits require further validation.

Lei Bao, Zhi-Fan Li, Xiao-Ning Liu et al. · 0 citations
Jul 2026

Associations between prediabetes, type 2 diabetes, and incident arrhythmias: a population-based cohort study and Mendelian randomization analysis.

Findings highlight the differential prognostic utility of ADA and WHO/IEC criteria for arrhythmia risk stratification: the ADA criteria offer broader sensitivity for early detection, whereas the stricter WHO/IEC criteria identify a higher-risk subgroup warranting more intensive management.

Yan-Jun Song, Zhihao Zheng, K. Cui et al. · 0 citations
Jul 2026

Evidence from two large prospective cohorts: variations in remnant cholesterol inflammation index and the risk of cardiometabolic multimorbidity in middle-aged and elderly populations.

By integrating lipid and inflammatory pathways, the RCII was significantly associated with incident CMM and may enhance early risk stratification and may enhance early risk stratification.

Song Wen, Zhonghua Sun, Yanjun Song et al. · 0 citations

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