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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

K. Dubey

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Review Open access Sep 2026

Structural insights into the bioengineering of heme-containing enzymes.

This review provides a comprehensive overview of the structural and mechanistic principles that underpin the bioengineering of heme proteins for both natural and abiological transformations, concluding that the core of reactivity of such metalloenzymes is the iron-porphyrin cofactor, whose tunable oxidation and spin st...

Epari Sai Santosh Kumar, K. Dubey · 0 citations
Review Open access Jul 2026

A Structural and Dynamic Perspective on Xenobiotic Metabolism by Cytochrome P450

Xenobiotic detoxification is the biotransformation of exogenous compounds entering the human body through enzymatic catalysis in order to assist their eventual elimination. In the past, static active-site models that mainly focus on substrate binding and oxidation chemistry have been employed to understand the xenobi...

Vaibhav Bhatt, K. Dubey · 0 citations

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