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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

K. Grafanaki

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2 papers indexed here

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Oct 2026

PNLDC1 deadenylase affects translational rate and cell proliferation in mESCs.

PNLDC1 is a member of the DEDD deadenylases, known for its specificity in poly(A) tail removal during mRNA turnover. While initially characterized for its function in pre-piRNA trimming critical to spermatogenesis and transposon silencing, its broader deadenylase activity which is especially pronounced during early dev...

Ilias Skeparnias, Athanasios-Nasir Shaukat, Christos Katsioulas et al. · 0 citations
Open access Sep 2026

A context-dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma.

Acquired resistance to vemurafenib, a BRAFV600E-targeted therapy, remains a major challenge in melanoma. The translation initiation factor eIF6 has been implicated in cancer; however, its role in vemurafenib resistance is poorly understood. We investigated eIF6 using melanoma cell lines with distinct mutational backgro...

G. Kyriakopoulos, Antonia Petropoulou, A. Anastogianni et al. · 0 citations

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