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Open access Aug 2026

Frontline daratumumab, lenalidomide, and dexamethasone in patients older than 80 years with newly diagnosed multiple myeloma: treatment durability, infectious complications, and nutritional vulnerability

Frontline DRd demonstrated favorable effectiveness and clinically meaningful treatment durability in patients aged > 80 years with Ti-NDMM and exploratory analyses suggested that a lower baseline PNI may be associated with severe infectious complications and a shorter treatment durability.

Yuichi Horigome, Koichi Ehata, N. Tadera et al. · 1 citation
Case report Open access Aug 2026

Disseminated varicella-zoster virus infection with gastrointestinal prodromal symptoms during daratumumab therapy for relapsed and refractory multiple myeloma

Varicella-zoster virus (VZV) reactivation is a recognized complication in patients with multiple myeloma, particularly during treatment-associated immunosuppression. Although disseminated VZV infection is uncommon, delayed diagnosis may result in life-threatening disease. We report a Japanese woman in her 70s with rela...

Yuichi Horigome, Yusuke Michishita, Momo Tanaka et al. · 1 citation

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