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K. Horiguchi

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Open access Aug 2026

METTL18 is Required for Developmental, Metabolic, and Endocrine Regulation of Mammalian Growth

Histidine methylation is an evolutionarily conserved but poorly understood post‐translational modification. METTL18 is known to catalyze histidine Nτ‐methylation in vitro, yet its physiological functions in mammals remain unclear. Here we show that mouse METTL18 possesses conserved histidine Nτ‐methyltransferase activi...

Fumiya Kasai, Jun-Dal Kim, K. Kako et al. · 0 citations

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