Real-World Safety and Effectiveness of Icatibant in Patients With Hereditary Angioedema (HAE): Post-Marketing Surveillance in Japan.
Hereditary angioedema (HAE) is a rare, autosomal dominant, life-threatening disease characterized by recurrent attacks of swelling of the face, upper airway, gastrointestinal tract, limbs, and/or genitalia. Genetic mutations of the SERPING1 gene encoding the C1-inhibitor (C1-INH) plasma protein are associated with HAE-...