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Open access Oct 2026

Src kinase as a molecular contributor to tau pathology in Alzheimer’s disease

Tau pathology is a defining feature of Alzheimer’s disease (AD), yet the molecular factors that modulate its onset and progression remain incompletely understood. The proto-oncogene Src kinase, a non-receptor tyrosine kinase with broad roles in neuronal signaling, has been implicated in neurodegenerative processes, b...

Diego Mastroeni, Chun-Kit Chan, Nader Morshed et al. · 0 citations
Open access Sep 2026

APOE-stratified genome-wide association analyses provide insights into the genetic etiology of Alzheimers’s disease

Understanding of the genetic architecture of AD in the context of its main genetic driver is improved, and APOE-stratified insights may help understand and overcome side effects, inform clinical trial enrollment strategies, and create the scientific basis for targeted, mechanism-driven therapies in neurodegenerative di...

J. Thomassen, H. Leonard, Brittany Ulms et al. · 0 citations

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